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Endometriosis Post. Bleeding after FIFTH Depot injection

By Anonymous June 19, 2013 - 12:50pm
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Hey guys,

I was diagnosed with Endo back in Nov 2012, bad times. I began Decapeptyl monthly - 6 month injection course and I recently (about 2 weeks ago) underwent my fifth injection. Up until then my periods were categorically abolished. Now however since 18th June, I have begun to bleed, almost like a light period, But why so LATE in the course?

Anybody else experienced this?


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Hello Anonymous,

You must contact your physician. Information provided on the website, netdoctor.co.uk., states that Decapeptyl is a gonadorelin analogue which acts on the pituitary gland. In the treatment of endometriosis, it is given as a monthly or three-monthly injection for six months, starting in the first five days of the menstrual cycle.

It should cause menstrual periods to stop. If you are experiencing menstrual bleed, now after five months, you should consult your doctor.

I do not know why this medication is not working to prevent your period. Please get back to us with your physician's explanation. I am curious.


June 19, 2013 - 4:47pm
EmpowHER Guest
Anonymous (reply to Maryann Gromisch RN)

Hi Maryann,

According to my Gynaecologist, who has a specialist area in Endometriosis, It's not uncommon at all, nothing at all to worry about, she didn't say why it was happening but I feel slightly reassured that she isn't too concerned. I intend to mention it to the nurse when I have my last injection and see if she thinks it would be worth requesting some sort of hormonal blood test. It is still strange but I'm less worried for sure.

June 21, 2013 - 1:32pm
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