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Ankylosing Spondylitis Causes & Risks


The cause of ankylosing spondylitis is not known. However, most people with ankylosing spondylitis share a common gene marker called HLA-B27. This finding indicates that genes play an important role in the development of this condition.

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.

  • Sex: male
  • Age: adolescent and young adult (ages 15-35)
  • Family members with ankylosing spondylitis
  • Having the HLA-B27 gene marker
  • Inflammatory bowel disease

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2022 EBSCO Publishing All rights reserved.

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