Progressive Multifocal Leukoencephalopathy: PML Facts
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Causes
PML is caused by a papovavirus, known as JC virus. Most people get this infection in childhood, and it produces no illness. It reactivates later in life in people who have a suppressed immune system (eg, HIV/AIDS ).
Risk Factors
The most common risk factor is having HIV/AIDS. PML has rarely been associated with:
- Leukemia and lymphoma
- Tuberculosis
- Sarcoidosis
- Prolonged immunosuppression (organ transplant or cancer patients)
- Chronic steroid therapy
- Rare inherited immunodeficiencies
- Natalizumab (medication used to treat multiple sclerosis )—the risk may only occur when also taking other immunosuppressants
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2024 EBSCO Publishing All rights reserved.