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Progressive Multifocal Leukoencephalopathy Symptoms & Diagnosis

Symptoms

If you experience any of these symptoms do not assume it is due to PML. These symptoms may be caused by other conditions. Symptoms progress over weeks and include:

  • Vision problems
  • Speech pronunciation problems
  • Ataxia (loss of coordination)
  • Memory loss
  • Weakness
  • Behavioral changes
  • Cognitive changes
  • Aphasia (loss of language capability)
  • Very rarely, seizures and headaches

Diagnosis

Your doctor will ask about your symptoms and medical history. She will also do a physical exam. Tests may include:

  • MRI scan —a test that uses magnetic waves to make pictures of structures inside the brain (key in the diagnosis)
  • Spinal tap —removal of a small amount of cerebrospinal fluid to check for evidence of the JC virus in the brain
  • Blood and urine tests
  • Brain biopsy

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. Copyright © 2019 EBSCO Publishing All rights reserved.

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