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Genetic Mutations That Affect Sleeping Hours

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Do you ever wish you could get a good night's rest on just a few hours of sleep? For some people, this is possible, due to a genetic mutation. ]]> Scientific American ]]> reveals that a mother and daughter both had a mutation of a gene that allowed them to sleep an average of 6.25 hours a night, and feel well rested and maintain good health. The gene? DEC2

Research on DEC2 has been conducted for a number of years, focusing on its role in sleep. Hamaguchi et al., authors of the article ]]> “Expression of the Gene for DEC2 , a Basic Helix-Loop-Helix Transcription Factor, is Regulated by a Molecular Clock System,” ]]> state that “it is known that mammalian circadian rhythms are controlled by molecular clockwork systems bases on negative-feedback loop(s), but the molecular mechanisms for the circadian regulation of DEC2 gene expression have not been clarified.” The research noted by Scientific American is the mutation of the DEC2 transcription facilitator is involved in the circadian clock.

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