New research has come in from the University of Rochester Medical Center suggesting that older adults who sleep poorly are at an increased risk of developing poor physical and psychological outcomes. This is due to their altered immune system response, which has resulted from the poor sleep pattern. (1)
A particular marker of inflammation associated with poor health and even death, interleukin 6 was found significantly higher in poor sleepers compared to the good sleepers.
Interleukin 6 is a protein found in our blood secreted by T cells which are a type of immune cells that stimulate immune response, inflammation being one such response.
According to assistant professor of Psychiatry at the Medical Center, Kathi L. Heffner, Ph.D, “This study offers more evidence that better sleep not only can improve overall well-being but also may help prevent poor physiological and psychological outcomes associated with inflammation. Our study suggests that, for healthy people, it all comes down to sleep and what poor sleep may be doing to our physiological stress response, our fight or flight response.” (2)
The research that was funded by a grant from the National Institutes of Aging and published in American Journal of Geriatric Psychiatry clearly suggested that though there were other factors of immune dysfunction such as depression, loneliness and perceived stress, it was poor sleep alone that caused a heightened inflammatory response to acute stress.
The study was conducted on 45 women and 38 men of a mean age of 61 years who were in good physical health. They were assessed for their cognitive status and sleep quality. The participants filled out a form on how they perceived stress, loneliness and medication use. Twenty-seven percent of the participants were found to be poor sleepers.
Just prior to the start of the study, blood samples were taken from the participants. Then the study began with the administration of tests that served as stressors (such as verbal tests, working memory tests and a battery of questions).
After this, a blood test was taken again of the volunteers, and again at three intervals spaced out over 60 minutes.