Erythema Multiforme

Erythema multiforme is a common skin disorder consisting of target-like circular lesions: red center, pale ring, and dark red outer ring. These lesions appear suddenly on the legs, arms, palms, hands, feet, and inside the mouth. Erythema multiforme minor is the most frequent form and is generally mild.

Erythema multiforme major, while rare, can be life-threatening. This severe form of the disorder usually causes target lesions with painful blisters at their center, which tend to appear on the trunk, eyes, inside the mouth, and genitals. It is also called Stevens-Johnson syndrome.