The information provided here is meant to give you a general idea about each of the medications listed below. Only the most general side effects are included. Ask your doctor if you need to take any special precautions. Use each of these medications only as recommended by your doctor, and according to the instructions provided. If you have further questions about usage or side effects, contact your doctor.
With progressive deterioration of kidney function, there needs to be an adjustment of either the dosage or the frequency of many drugs which depend on normal renal function for their elimination from the body. These drugs include the following:
If you have
high blood pressure
diabetes, medications will likely be ordered to control these conditions. Leakage of protein from the urine (proteinuria) is treated with two drugs used in the treatment of high blood pressure: ACE inhibitors and angitensin receptor blockers (ARBs). In addition, medications may be needed to treat complications of kidney disease. There are no medications to cure or reverse kidney failure.
In chronic renal disease, a disturbance in calcium, phosphate, and vitamin D metabolism lead to a condition called secondary
, which is characterized by abnormally high levels of parathyroid hormone (PTH) levels in the blood. The high PTH levels lead to uremic bone disease. A recently approved drug, Cinacalcet HCL is effective in lowering the elevated PTH levels in chronic renal failure patients. It is taken by mouth.
This drug is injected and used to treat anemia associated with renal failure. It stimulates production of red blood cells.
Possible side effects include:
Increased blood pressure
Typically taken orally, sodium bicarbonate may be ordered if you develop a condition called metabolic acidosis, which is an excess of acid in the blood due to alterations in metabolism from kidney failure.
If you need to use sodium bicarbonate, you should review your dietary sodium intake with your physician or dietician, since this medication will increase the sodium in your diet.
Calcium Carbonate or Calcium Acetate
Calcium supplements are given to bind phosphate in order to maintain phosphate levels within a range that will not increase bone loss. These drugs are taken orally.
Possible side effects include:
Loss of appetite
Slow heart rate
Whenever you are taking a prescription medication, take the following precautions:
Take your medication as directed. Do not change the amount or the schedule.
Do not stop taking them without talking to your doctor.
Do not share them.
Know what the results and side effects may be. Report them to your doctor.
Some drugs can be dangerous when mixed. Talk to a doctor or pharmacist if you are taking more than one drug. This includes over-the-counter medication and herb or dietary supplements.
Plan ahead for refills so you don’t run out.
When to Contact Your Doctor
Call your healthcare provider if you develop side effects from the medications or experience:
Signs of infection, including fever and chills
Nausea or vomiting
Dizziness or weakness
Coladonato JA. Control of hyperphosphatemia among patients with ESRD.
J Am Soc Nephro.
Malluche HH, Mawad H, Monier-Faugere MC. The importance of bone health in end-stage renal disease: out of the frying pan, into the fire?
Nephrol Dial Transplant.
Torres PU. Cinacalcet HCL: a novel treatment for secondary hyperparathyroidism caused by chronic kidney disease.
J Ren Nutr.
Yu HT. Progression of chronic renal failure.
Arch Int Med.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a