is a condition marked by very high
levels of protein in the urine; low levels of protein in the blood;
swelling, especially around the eyes, feet, and hands; and high
cholesterol. Nephrotic syndrome results from damage to the kidneys'
glomeruli (the singular form is glomerulus). Glomeruli are tiny
blood vessels that filter waste and excess water from the blood and
send them to the bladder as urine.
Nephrotic syndrome can occur with many diseases, including the
kidney diseases caused by diabetes mellitus, but some causes are
unknown. Prevention of nephrotic syndrome relies on controlling
Treatment of nephrotic syndrome focuses on identifying the
underlying cause if possible and reducing high cholesterol, blood
pressure, and protein in urine through diet, medications, or both.
One group of blood pressure medications called ACE inhibitors also
protects the kidneys in diabetic patients.
Nephrotic syndrome may go away once the underlying cause, if
known, has been treated. However, most of the time a kidney disease
is the underlying cause, and these diseases cannot be cured. In
these cases, the kidneys may gradually lose their ability to filter
wastes and excess water from the blood. If kidney failure occurs,
the patient will need dialysis or a kidney transplant.
Please be aware that this information is provided to supplement the care
provided by your physician. It is neither intended nor implied to be a
substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER
IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the
advice of your physician or other qualified health provider prior to
starting any new treatment or with any questions you may have regarding a
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