1) Ovarian cancer is the fifth most common cancer among women. An estimated 21,990 new cases will be diagnosed in the United States in 2011. More women die of ovarian cancer than any other type of female reproductive cancer. Approximately 15,460 women will die of ovarian cancer this year.
2) Ovarian cancer forms in the tissue of the ovary, which is one of a pair of female reproductive glands. The ova or eggs are stored and released each month from the ovaries. The ovaries produce the two female hormones, estrogen and progesterone.
3) There are three main types of ovarian tumors. Epithelial ovarian tumors are the most common type, form in the cells on the surface of the ovary and occur primarily in adults. Germ cell ovarian tumors are rare, beginning in the egg cells within the ovary and occurring primarily in children and teens. Sex cord stromal ovarian tumors are rare and form in the ovarian tissue which produces estrogen and progesterone.
4) An inherited gene mutation accounts for a small percentage of ovarian cancers. Two genes, BRCA1 or breast cancer gene 1 and BRCA2 or breast cancer gene 2 were originally identified in families with multiple cases of breast cancer. A significant increased risk for ovarian cancer has been identified in women with these gene mutations. Another known genetic link involves hereditary nonpolyposis rectal cancer and the increased risk for ovarian, endometrial, colon and stomach cancers.
5) A family history of ovarian cancer, a previous diagnosis of cancer, advanced age and never having been pregnant are risk factors which increase a woman's chance of developing ovarian cancer. There are inconsistent findings regarding the correlation between menopausal hormone therapy and the increased risk of ovarian cancer.
6) The symptoms often mimic symptoms of bladder and digestive system disorders. Abdominal bloating, pelvic pain, persistent indigestion and gas, changes in bowel habits, increase in abdominal girth, increased urinary urgency and frequency, loss of appetite, low back pain and persistent lack of energy are symptoms a woman must be cognizant of.