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Vitamin D Deficiency and Thyroid Disease

 
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Vitamin D is an important vitamin that not only regulates calcium, but also has many other beneficial actions. Not many endocrinologists realize this, but several articles published over 20 years ago showed that patients with hypothyroidism have low levels of vitamin D.

This may lead to some of the bone problems related to hypothyroidism. It was thought that one of two mechanisms may explain the low levels of vitamin D in patients with hypothyroidism, 1) the low levels of vitamin D may be due to poor absorption of vitamin D from the intestine or 2) the body may not activate vitamin D properly. Other articles have demonstrated that patients with Graves disease also have low levels of Vitamin D.

Importantly, both vitamin D and thyroid hormone bind to similar receptors called steroid hormone receptors. A different gene in the Vitamin D receptor was shown to predispose people to autoimmune thyroid disease including Graves’ disease and Hashimoto’s thyroiditis. For these reasons, it is important for patients with thyroid problems to understand how the vitamin D system works.

Sources of Vitamin D

Vitamin D is really two different compounds, ergocalciferol (vitamin D2), found mainly in plants and cholecalciferol (vitamin D3), found mainly in animals. Both of these hormones are collectively referred to as vitamin D, and they can either be obtained in two ways. One is by exposure of the skin to the ultraviolet (UV) rays of sunlight or also from dietary intake.

Vitamin D is found naturally in fish (such as salmon and sardines) and fish oils, eggs and cod liver oil. However most Vitamin D is obtained from foods fortified with Vitamin D, especially milk and orange juice. Interestingly, as breast feeding has become more popular, the incidence of Vitamin D deficiency has increased as less fortified milk is consumed.

Vitamin D deficiency may also occur in patients with malabsorption from their intestine, such as in the autoimmune disease called Celiac Disease, which occurs frequently in patients with thyroid problems. Multivitamins also contain Vitamin D, as does some calcium supplements like Oscal-D and Citracal plus D.

Add a Comment10 Comments

EmpowHER Guest
Anonymous

Vitamin d deficiency had been common in most of the people.. I wish everyone should have some knowledge to over come the problems.

Thanks for sharing

November 4, 2013 - 3:50am
EmpowHER Guest
Anonymous

Other articles have demonstrated that patients with Graves disease also have low levels of Vitamin D.

August 6, 2013 - 11:58pm
EmpowHER Guest
Anonymous

Thank you for your article however there is one point which I disagree with.

Your inference that vitamin D could relate to increased breast feeding is I think and bad inference to make to mothers. There are so many benefits from breast feeding and so many negatives attached to formula that you just have to look at the third world (yes even if we have better water although that could be debated). What you will find is a bigger correlation between vitamin D.

August 3, 2013 - 5:05am

i never knew vitamin d deficiency could cause thyroid problems. what is the best way to treat this? Exposure to sunlight?

August 13, 2010 - 11:05am
EmpowHER Guest
Anonymous

Well, to make the long story short, my friend had thyroid problems. Later they found out he has some nodules in her thyroid too. After that he was diagnosed with Vitamin D deficiency. She had never heard of such thing. It's always about checking her cholesterol and all that, but never anyone told her to check her vitamin d level.
SO the lesson here is to have your levels checked by your doctor!

June 15, 2010 - 7:13pm
EmpowHER Guest
Anonymous

There is a mistake in your article.

Dr., You've mixed up your Vit. D types. In the article you say, " cholecalciferol (vitamin D2) and ergocalciferol (vitamin D3)." You have it reversed. Actually, Vit. D3 is cholecalciferol and Vit. D2 is ergocalciferol.

If you need extra proof, just check out the National Osteoporosis Foundation's website at http://www.nof.org/prevention/vitaminD.htm

June 25, 2009 - 7:33am
EmpowHER Guest
Anonymous

I am a gastric bypass patient of 5 years. My vitamin D -25 hydroxy levels was a 5. My question is if I can not absorb the 50,0000 IU am i just taking pils? I am in alot of pain and aches with my joints and hand and leg pain and have family history of arthritis, and cushing syndrom and ankloysis.
What do i do or what r my options? I have an appt with Endo in a month....thanks Ann

April 18, 2009 - 3:34pm
EmpowHER Guest
Anonymous

Mothers that are breast feeding and are worried about the lose of D-3. Just get the baby out in the sun when possible.............Pete

March 29, 2009 - 9:01am
EmpowHER Guest
Anonymous

I understand the concern that vitamin D deficiency in infants may increase with breast feeding may be misconstrued as advice against breast feeding babies. What I think the point here is that if a mother is breast feeding, she should also give her child a vitamin D supplement in addition to breast milk rather than forgo breast feeding the baby.

It amazes me that the importance of vitamin D has been so ignored. I have just been floored by the articles that have been coming out the last two years relating low vitamin D to everything from diabetes to MS to obesity to stroke to heart disease to back pain to cancer. Now thyroid disease too. How much money could we save on medical treatment and improve our quality of life just by taking a cheap vitamin D supplement? I started.

March 29, 2009 - 7:53am
EmpowHER Guest
Anonymous

Dear Dr Friedman,

Thank you for your article however there is one point which I disagree with.

Your inference that vitamin D could relate to increased breast feeding is I think and bad inference to make to mothers. There are so many benefits from breast feeding and so many negatives attached to formula that you just have to look at the third world (yes even if we have better water although that could be debated). What you will find is a bigger correlation between vitamin D deficiency and the use of sun block (particularly on children) and the common vitamin D deficiency past on from parent to child. Pre conception health of both parents is key.

March 28, 2009 - 8:01am
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We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

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