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What medications are damaging to kidneys?

By Anonymous April 27, 2015 - 7:30am
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Hello Anonymous,

That is a very good question. Medications are a common source of acute kidney injury.

Risk factors for drug-induced nephrotoxicity are age, specifically individuals older than 60 years, underlying renal insufficiency , volume depletion, diabetes, heart failure, and sepsis.

Drugs associated with causing nephrotoxicity include:
analgesics: acetaminophen, aspirin, nonsteroidal anti-inflammatory drugs

antidepressants/mood stabilizers: Amitriptyline (Elavil*), doxepin (Zonalon), fluoxetine (Prozac),Lithium

antihistamines: Diphenhydramine (Benadryl), doxylamine (Unisom)

antimicrobials: Acyclovir (Zovirax), Aminoglycosides

I hope this was the information you are looking for.


April 27, 2015 - 9:24am
EmpowHER Guest
Anonymous (reply to Maryann Gromisch RN)

Great info. Can too many vitamins hurt your kidneys?

April 27, 2015 - 9:55pm
Guide (reply to Anonymous)

Hello Anonymous,

By reviewing scholarly medical articles, I found an article in the Clinical Journal of the American Society of Nephrology. This is the link if you are interested in reading full article.

"In all cases, the administration of high-dosage vitamin C (nearly 60 g/d) resulted in extensive oxalate deposition in the renal tubules with associated acute tubular necrosis. Vitamin C is metabolized to several byproducts, including oxalate, before elimination via filtration and tubular reabsorption."


April 28, 2015 - 8:55am
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