Dr. Sitruk-Ware shares if there are any new male contraceptive methods in development.
At the Population Council, we are working on a new method for male contraception using an implant which will be inserted under the skin of the arm and delivers a male hormone. The name of that hormone is MENT, and this hormone has a specific profile, does not stimulate the prostate growth, and this is an advantage compared to the normal male hormone which may lead with age and long-term therapy to increase the growth of the prostatic cells.
So we are working with several clinics where we tested these implants which are produced in this very lab, and these implants will deliver sufficient hormones to replace the androgen of the men because we are blocking their own function and we block the sperm production so then they will become as azospermic (without sperm) and they would not be able to fertilize the egg. And therefore they would not be able to induce a pregnancy. This is a method which is now in the advanced stage of development. We are finalizing better prototype of implants for the next clinical studies.
About Dr. Sitruk-Ware, M.D.:
Dr. Régine L. Sitruk-Ware is a reproductive endocrinologist and the executive director of research and development at the Population Council’s Center of Biomedical Research. She supervises the basic research in reproductive biology as well as the pre-clinical research and clinical development of new molecules designed for reproductive healthcare in men and women suitable for use in developing countries. Prior to joining the Council, she had a successful academic career in Paris, France and then an international career in research and development. She taught and conducted clinical research in reproductive endocrinology at the University of Paris for ten years. From 1983 to 1989 she was a member of the International Committee for Contraceptive Research (ICCR), established by the Population Council in 1970. RSW is now chairing the ICCR since January 2007. She is a member of several national and international medical societies. She has been a founding member of the International Menopause Society and a member of its Board for several terms and is presently the General Secretary of that society. She is also member of the Expert group on Hormonal Contraception of the European Society for Contraception. She is the Program Director and Principal Investigator of a NIH Center grant from the National Institute of Child Health and Human Development.
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