Hide This

FREEHER HealthToolkit

HER Health Toolkit

Sign up for EmpowHER updates and you'll receive our
FREE HER Health Toolkit

Alzheimer's Disease

Get Email Updates

Alzheimer's Disease Guide

Alison Beaver

Have a question? We're here to help. Ask the Community.

ASK

Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!

Alzheimer’s: Is It A New Type Of Diabetes?

By Katie Meakem
 
Rate This
Alzheimer’s: Is It A New Type Of Diabetes? 5 5 2
brain's resistance to insulin
Sergey Nezhinkiy/PhotoSpin

The brain's resistance to the action of insulin can lead to cognitive decline experienced in Alzheimer's sufferers, according to recent research.

Correlating the brain and insulin response has coined the term "type 3 diabetes" for Alzheimer's disease. But will the name stick?

Rhode Island Hospital researcher, Suzanne de la Monte, M.D., found a link between diabetes and mediators of neuronal injury that help Alzheimer’s disease spread.

The ability of the brain to respond to insulin is important for normal function but is resisted at some point, according to the research. This is why it is associated with the symptoms found in Alzheimer’s sufferers.

The University of Pennsylvania’s study, the first to show that insulin resistance occurs, indicated that Alzheimer’s could develop without a significant amount of hyperglycemia (increased blood sugar).

The researchers tested the brains of deceased non-diabetic patients with Alzheimer's disease to demonstrate that even with normal blood sugar levels, those brains showed that they were resistant to insulin activation.

Type 1 and type 2 diabetes are characterized by hyperglycemia. The term "Alzheimer’s type 3 diabetes" was coined to differentiate those who did not activate various proteins in the insulin-signaling pathways, but may have normal blood sugars.

According to Diabetes.co.uk, those with insulin resistance increase their risk of Alzheimer’s by about 50 to 65 percent.

The University of Pennsylvania research showed that type 2 diabetics produce protein deposits, known as amyloid beta, in their pancreases. These protein deposits are analogous to those found in the brain tissue of Alzheimer’s patients.

Alzheimer’s disease occurs when nerve cells in the brain die, inhibiting brain signaling. There is no definitive test for Alzheimer's disease.

The symptoms of Alzheimer’s disease include problems with memory, judgment and thinking, according to WebMD.com.

Nerve cell death occurs gradually over a period of years. The course of Alzheimer's disease could last from two to three years or as long as 20 years, according to WebMD.com.

Add a Comment1 Comments

EmpowHER Guest
Anonymous

It is amazing that more has not been done in Washington to help fight this illness. The link to blood sugar is interesting although I am not sure that the illness is a new form of diabetes. I have learned that when the illness hits close to home much needs to be done.
my mother has dementia

April 10, 2013 - 5:42pm
Image CAPTCHA
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Improved

1703 Health

Changed

641 Lives

Saved

497 Lives
7 lives impacted in the last 24 hrs Learn More

Take Our Featured Health Poll

Do your teens have their own cellphones?:
View Results