Hide This

FREEHER HealthToolkit

HER Health Toolkit

Sign up for EmpowHER updates and you'll receive our
FREE HER Health Toolkit

Chronic Myelogenous Leukemia

Get Email Updates

Related Topics

Chronic Myelogenous Leukemia Guide

Maryann Gromisch RN Guide

Have a question? We're here to help. Ask the Community.

ASK

Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!

Study: Revolutionary Treatment Returns Normal Life Expectancy to CML Patients

By Pat Elliott HERWriter Guide
 
Rate This

New research confirmed that a revolutionary drug has transformed a previously fatal leukemia into a manageable chronic disease for many patients. The drug, imatinib (brand name: Gleevec), was approved by the United States Food and Drug Administration in 2001 for patients with chronic myelogenous leukemia (CML), a cancer of the white blood cells.

Researchers found patients taking imatinib for CML, who have been in cytogenic remission after two years of treatment, have a mortality rate similar to that of the general population. For patients this provides the first clear evidence that the drug is able to control their cancer in a way that gives them a normal life expectancy. The Long Term Imatinib Effects (ILTE) study was published online March 22, 2011 in the Journal of the National Cancer Institute. Data came from patients from 27 centers in Europe, North and South America, Africa, the Middle East and Asia.

According to the National Cancer Institute, “Imatinib represents a new class of cancer drugs and a new way of thinking about cancer. These molecularly targeted drugs are different because they target abnormal proteins that are fundamental to the cancer itself.”

Multiple studies of imatinib have taken place during industry-sponsored clinical trials at medical centers in the United States and other countries. This research was set up to study patients taking the drug as part of their daily lives instead of during clinical trials. Led by Carlo Gambacorti-Passerini, M.D. of the University of Milano Bicocca/San Gerardo Hospital in Monza, Italy, the study followed some 800 patients who were in complete cytogenic remission after two years of taking the drug. The mortality rate for those studied was 4.8 percent, which is similar to what would normally be expected in the general population.

The authors concluded that patients on imatinib “frequently suffer from side effects that are non-serious but can nonetheless reduce their quality of life.” They noted that the findings highlight the “importance of a good relationship between health care providers and patients, where side effects are easily communicated and addressed to reduce/avoid non-compliance.”

Add a Comment5 Comments

Arshad Khan

i was smoking alot before the diagnose of cml. Now i am taking gleevic So sometime i need to smoke... or to use tobacco >> is it harmful with gleevic??

December 10, 2012 - 1:54am
Pat Elliott HERWriter Guide (reply to Arshad Khan)

Smoking is a known cause of cancer. It is harmful with or without any type of medication.

December 10, 2012 - 8:03pm
Pat Elliott HERWriter Guide

Hi Arshad - It's not easy to hear that you have cancer but one thing you need to understand is that you did not cause this. The initial treatment period can be rough, but it does get better and better with time.

In terms of the cost of your medication, I suggest you contact the Max Foundation http://www.themaxfoundation.org/ which serves CML patients in need internationally.

All the best to you,
Pat

December 6, 2012 - 8:54pm
Arshad Khan (reply to Pat Elliott)

thanks pat!

December 10, 2012 - 1:48am
Arshad Khan

hi Pat Elliott ,,, it was going my normal life i have never felt pain or any difficulties in working , studing or walking ,,,But its reality that i was not taking breakfast at morning some time i was careless about my proper time food i was very careless to eat at time. some time to stop my food for 2 days ... and this was going on.....
then i felt that i am losing my wight ,, so i was worried about that situation ...
,,, and at the same time i am a student of Masscommunication ,,, i was writting my thesis somtime for late night ... so not taking food normally and lake of sleeping... and using of tabaco (smoking)... it became my rutien,,,
before 3 weeks i felt that my head is flying (hhahahaahh) and body is not in my control... so then i get fever and i was increase up to 103..104.. then i went hospital...Dr testet my blood for dengue..thypiod,,,malirya.. but it was nagitive ,,,then dr recoment CBC and it was daignose that i have cancer of blood...
when they announced and told me that i have cancer i can,t express my feeling in words i felt that the world which i have made for my life has been demalished and it was feeling like a juge santence a person that he will be hang 2 days after...
.now i am worring only about that glivec is too much highly priced tablets how can i countinue ... plz tell me ?? plz i want life i want life.....
i belong to meddle class familly which pay me to countinue my studies hardly...
from pakistan...swat..kpk...recently ...karachi

December 6, 2012 - 2:59am
Image CAPTCHA
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Improved

1879 Health

Changed

774 Lives

Saved

641 Lives
8 lives impacted in the last 24 hrs Learn More

Take Our Featured Health Poll

Do your teens have their own cellphones?:
View Results