Neurofibromatosis

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Neurofibromatosis Definition

Definition

Neurofibromatosis (NF) is a genetic disorder of the nervous system. It causes tumors to grow on the nerves in any part of the body. NF can also produce other abnormalities, such as:

  • Changes in skin color
  • Deformity of bones

The Nervous System

Nucleus factsheet image
© 2009 Nucleus Medical Art, Inc.

There are two types:

  • NF1—caused by mutations (or changes) of the neurofibromin gene (more common)
  • NF2—caused by mutations of the merlin gene

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Neurofibromatosis Guide

Alison Beaver

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