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Pemphigus

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Pemphigus Definition

Definition

Pemphigus is a group of rare autoimmune disorders. It causes large skin blisters. The immune system normally protects against germs and other foreign invaders. In this case, the immune system mistakenly attacks your own skin and mucus membranes. There are three forms of the disease:

  • Pemphigus vulgaris—most common type of pemphigus; lesions may extend deep into the layers of the skin
  • Pemphigus foliaceus—produces more superficial lesions
  • Paraneoplastic pemphigus—most serious type; usually occurs in someone who has cancer

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