PhyllanthusPhyllanthus amarus, Phyllanthus niruri, Phyllanthus urinaria
Tropical plants in the genus
have a long history of use in
What Is Phyllanthus Used for Today?
P. amarus has undergone considerable evaluation as a as a treatment for chronic hepatitis B, and a bit of study for acute hepatitis. However, the results have not been promising. The current consensus is that the herb is not helpful for hepatits. P. urinaria also appears to be ineffective.
What Is the Scientific Evidence for Phyllanthus?
Despite numerous test tube and animal studies showing efficacy against the hepatitis B virus, 2
Only one study clearly found benefits, and it was seriously flawed. In this 30-day
However, the high drop-out rate in the
Another double-blind, placebo-controlled trial enrolled 57 people with acute hepatitis B to see whether treatment with
(300 mg 3 times daily for 1 week) could improve speed of recovery.
One highly preliminary study suggested that
, a related species, might be more effective against hepatitis than other species of phyllanthus.
There are no indications that P. amarus is toxic when used at recommended doses, but comprehensive safety studies have not been performed. 14 In double-blind studies, significant side effects have not been reported. Safety in pregnant or nursing women, or individuals with severe liver or kidney disease, has not been established.
13. Wang M, Cheng H, Li Y, et al. Herbs of the genus phyllanthus in the treatment of chronic hepatitis B: observation with three preparations from different geographic sites. J Lab Clin Med . 1995;126:350–352.
Last reviewed April 2009 by EBSCO CAM Review Board
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2007 EBSCO Publishing All rights reserved.