Dr. Heward explains if oral or transdermal hormones are the most effective administration to receive the optimal hormone balance.
The most effective form of administration is completely a function of the individual who is taking the hormone because you, as a woman, have to decide what you mean by "effective." Physiologically, the hormones are going to get in to the system whether it's oral or transdermal, and they’re going to have their impact on the receptors in a way that produces the results that you want them to produce, but depending upon your situation, you may have a problem with a first-pass effect of the hormone on the liver, and so, for you, the transdermal preparation maybe more important.
In another individual, you may find the transdermal messy and not easy to administer, and the dose is difficult to regulate or it’s a pain in the butt for you, and it’s just so much more convenient to take the oral preparation, that’s what you prefer, then that’s what you want to do.
What you don’t want to do is get fixated in advance on a preparation that is bioidentical, for example, simply because it must be, and then make the wrong decision because you can’t find a formulation of bioidentical hormone that works for you. Other things being equal, it seems intuitively obvious that to the extent that you can mimic youthful norms, having hormones that are identical to what they were when you were producing them yourself and in patterns that were comparable with what you produced when you were young, that would be the best of all worlds and that would tend to be bioidentical transdermal.
About Dr. Heward, Ph.D:
Dr. Christopher B. Heward is past-President of Kronos Science Laboratory. His primary responsibility was providing scientific and technical leadership for all laboratory activities. He oversaw the development and implementation of the clinical laboratory testing program; assisted in designing and refining both internally and externally sponsored clinical studies; directed and coordinated diagnostic product research and development; administered laboratory and patient databases; was principal investigator for the Kronos Longitudinal Aging Study (KLAS); and communicated Kronos’ discoveries and advances to lay and scientific audiences via presentations and publications. Dr. Heward’s research interests included healthy aging, endocrinology, oxidative stress, Alzheimer’s disease, prion disease (TSE) and menopause. Dr. Heward attended the University of Arizona and received a Bachelor of Arts degrees from both the Department of Psychology and the Department of Chemistry, as well as a Bachelor of Science degree from the Department of Biology. He earned his PhD from the Department of Biology in 1981.
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