Dr. Sitruk-Ware explains if there is a relationship between ovarian cancer and hormone replacement therapy (HRT).
I can answer no. It’s difficult to say because ovarian cancer is difficult to diagnose, but estrogen have never been shown to increase the risk of ovarian cancer. Estrogens are possibly increasing endometrial cancer if they are not balanced by progesterone or progestins. They may stimulate a small breast cancer, reveal an existing breast cancer and stimulate the cell multiplication, but there were no indication on a relationship with the ovarian cancer.
About Dr. Sitruk-Ware, M.D.:
Dr. Régine L. Sitruk-Ware is a reproductive endocrinologist and the executive director of research and development at the Population Council’s Center of Biomedical Research. She supervises the basic research in reproductive biology as well as the pre-clinical research and clinical development of new molecules designed for reproductive healthcare in men and women suitable for use in developing countries. Prior to joining the Council, she had a successful academic career in Paris, France and then an international career in research and development. She taught and conducted clinical research in reproductive endocrinology at the University of Paris for ten years. From 1983 to 1989 she was a member of the International Committee for Contraceptive Research (ICCR), established by the Population Council in 1970. RSW is now chairing the ICCR since January 2007. She is a member of several national and international medical societies. She has been a founding member of the International Menopause Society and a member of its Board for several terms and is presently the General Secretary of that society. She is also member of the Expert group on Hormonal Contraception of the European Society for Contraception. She is the Program Director and Principal Investigator of a NIH Center grant from the National Institute of Child Health and Human Development.
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