Dr. Sitruk-Ware shares how the hormones estrogen and progesterone interact in women.
Estrogen is the key hormone that leads to the development of the breast, the increasing growth of the urogenital tract, which means the vagina, the uterus, and improve the skin aspect, the hair growth. There are estrogen receptors in many parts of the body, also in the vessels, in the bone, in brain, and the progesterone is the hormone which is secreted when an ovulation takes place and when the women are during their fertile years, they have every month, an ovulation and a secretion of progesterone 15 days per month.
This hormone balances the estrogenic action on the uterus, on the breast, on the brain, on the vessels. They are two complementary hormones, and they are balancing each other. Estrogen is the hormone of tissue growth, and progesterone is a hormone of differentiation of the tissue to make it functional. For example, for the breast to have all of the ducts developed in terms of preparation for lactation as an example. So these two hormones are needed for the balance of all the tissues in the body of the woman.
About Dr. Sitruk-Ware, M.D.:
Dr. Régine L. Sitruk-Ware is a reproductive endocrinologist and the executive director of research and development at the Population Council’s Center of Biomedical Research. She supervises the basic research in reproductive biology as well as the pre-clinical research and clinical development of new molecules designed for reproductive healthcare in men and women suitable for use in developing countries. Prior to joining the Council, she had a successful academic career in Paris, France and then an international career in research and development. She taught and conducted clinical research in reproductive endocrinology at the University of Paris for ten years. From 1983 to 1989 she was a member of the International Committee for Contraceptive Research (ICCR), established by the Population Council in 1970. RSW is now chairing the ICCR since January 2007. She is a member of several national and international medical societies. She has been a founding member of the International Menopause Society and a member of its Board for several terms and is presently the General Secretary of that society. She is also member of the Expert group on Hormonal Contraception of the European Society for Contraception. She is the Program Director and Principal Investigator of a NIH Center grant from the National Institute of Child Health and Human Development.
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