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High SGPT & GGT levels

By Anonymous July 28, 2010 - 1:35pm
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The following describes the chronological status of my results and i hope to have a comforting response from you:

1. January 16th 2010: Had a full blood check up and i noticed the following:
SGPT (ALT): 233.2
SGOT (AST): 81.2
Serum Alk. Phosphatase: 203

Accordingly i went to a liver specialist and had an ultrasound which concluded an enlarged liver size 18cm and i was told that i have what is called a "Fatty Liver". Then i was asked to have some medicine and to have a check for Viruses A,B & C in addition to SGPT, SGOT and GGT

2. February 15th 2010, i did the lab tests, and the results were as follows:
Viruses were negative
SGPT (ALT): 163
SGOT (AST): 61
GGT: 356

i was terrified by the GGT but the Dr told me that this number will be lowered after the enzymes are back to their normal range.
I was also given some more meds for an additional 2 months.

3. April 4th 2010

I had the lab tests results as follows:
SGPT (ALT): 63.4
SGOT (AST): 78.5
GGT: 537

i was still terrified of the number, but the Dr comforted me and told me that this is normal, but he modified the medicine to lower the GGT and asked me to come back after 2 weeks.

4. April 20th 2010
I had the lab tests results as follows:
SGPT (ALT): 133.4
SGOT (AST): 69
GGT: 410

At this point i decided to visit another specialist to have a second opinion, who ordered additional tests (SGPT, GGT, ANA, LKM -Ab, AMA & ASMA) and gave me a couple of meds to have and asked me for a strict food diet for the remainder of the month.

4. May 26th 2010: Donated blood for an open heart surgery patient ( the hospital made a full viruses lab test for the blood and they told me that every thing is ok)

5. June 09th 2010

results as follows:
SGPT(ALT): 124.8
GGT: 312

ANA by IF: Negative
AMA: Negative
LKM - Ab: Negative
ASMA: Positive

6. July 5th 2010
SGPT(ALT): 119
GGT: 212

Finally, My Doctor comforted me that this is just a genetic related disease and that i do not need to worry.
My question is, Should i be alarmed or not, even though my doctor diagnosis is decreasing the enzymes?

Add a Comment3 Comments

HERWriter Guide

Hi Moataz - I can't tell you what you should do...but...if I had a health problem involving my liver, and I wasn't getting the information and support I needed from the medical specialists I was seeing, I would find the most qualified expert in my local area and make an appointment, even if I had to do so at my own expense. We only get one body and we only go around once, and the ride is sure a lot better when we're healthier, right?

A non fat diet and lots of sports, of course, is wonderful, but if I'm understanding you correctly you would really like to have a much better understanding of the exact status of your health.

I have sometimes found that seeing the nurse practitioner in my primary care doctor's office has been helpful when I need more of an explanation of what I'm dealing with, and that I get more time with her than I typically do with my doctor, so that's another route to consider.

Hope that helps, and good luck!

August 5, 2010 - 5:36pm
HERWriter Guide

Anon - There are two types of fatty liver disease - one type is related to a history of using alcohol and the other type is not.It sounds like your doctor hasn't provided much information and that you have a lot of questions. It also sounds like your doctor is monitoring your medical condition closely and is not expressing alarm.

Since you haven't mentioned alcohol issues, I'm going to assume you have nonalcoholic fatty liver, but if this is wrong just let us know.

Here are some resources for more information to better understand what causes this, how it is treated, how it impacts your lifestyle and more.



As you will see in the information, treating this condition can be complex and may require a lot of adjustments. EmpowHER does not provide medical diagnostic advice and we are not able to provide interpretation of your results. The information in the articles should help, and you may also want to check out a site which we like that provides in-depth information about lab test results which is at http://www.labtestsonline.org/
The site includes a section on liver disease.

Without treatment of course liver disease can progress and lead to serious illness. It's good that you are working with specialists, and I hope this additional information will give you more peace of mind.

Take care,

July 28, 2010 - 6:42pm
EmpowHER Guest
Anonymous (reply to Pat Elliott)

Thanks for your response.
However, i did try a certain trial to see the effect of food ( let me call it junk food) on my lab tests. I started eating normally or how i used to eat for a week and then went for a lab test and my results were as follows:
SGPT (ALT): 140.5
GGT: 226
(slightly elivated from last results)
Frankly, this is becoming very annoying, since i do not complain from any symptoms. Do you believe that i should look for a third opinion or should i just drop this issue and just stick to a non fat diet and lots of sports.

Thanks again

August 3, 2010 - 12:44pm
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