Moclobemide

Canadian Brand Names

Apo-Moclobemide®; Dom-Moclobemide; Manerix®; Novo-Moclobemide; Nu-Moclobemide; PMS-Moclobemide

Mexican Brand Names

Aurorex; Feraken

Pharmacologic Category

Antidepressant, Monoamine Oxidase Inhibitor, Reversible

Reasons not to take this medicine

• If you have an allergy to moclobemide or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have severe liver disease or uncontrolled high blood pressure.

• If you are taking any of these medicines: Bupropion, dexfenfluramine, dextromethorphan, guanethidine, meperidine, or any stimulant or depressant.

• If you are taking any of these medicines: Citalopram, fluvoxamine, paroxetine, or sertraline. Do not use within 2 weeks of other antidepressants.

• Fluoxetine should be stopped for at least 5 weeks before starting this medicine.

• If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this medicine is started. Taking the two together could cause dangerously high blood pressure.

What is this medicine used for?

• This medicine is used to treat depression.

How does it work?

• Moclobemide increases chemicals in the brain.

• In depression, sleep and appetite may improve quickly. Other depressive symptoms may take up to 4-6 weeks to improve.

How is it best taken?

• To gain the most benefit, do not miss doses.

• Take this medicine with food to prevent stomach upset.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Take a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not take a double dose or extra doses.

• Do not change dose or stop medicine. Talk with healthcare provider.

What are the precautions when taking this medicine?

• Wear disease medical alert identification.

• If you have liver disease, talk with healthcare provider.

• If you have pheochromocytoma, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Tell dentists, surgeons, and other healthcare providers that you use this medicine.

• Do not use over-the-counter medicines containing dextromethorphan or pseudoephedrine.

• If you are taking this medicine and have high blood pressure, talk with healthcare provider before using over-the-counter products that may increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain natural products or supplements.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• Avoid alcohol (includes wine, beer, and liquor).

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Headache.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

• Inability to sleep.

• High blood pressure can rarely occur.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Check blood pressure and heart rate regularly

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

• Follow up with healthcare provider.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• If you are planning to harm yourself or the desire to harm yourself increases.

• Chest pain or pressure, fast heartbeat, or passing out.

• Confusion; very nervous; anger with sweating, shivering, stiffness, or shaking.

• Severe headache.

• Severe nausea or vomiting.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?

• Store at room temperature.

• Protect from moisture. Do not store in a bathroom or kitchen.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

• Read the package insert for more details.

Created: 2008-01-16 08:11:42.0

Modified: 2008-02-04 14:43:18.0

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