Promethazine

U.S. Brand Names

Phenadoz™; Phenergan®; Promethegan™

Canadian Brand Names

Bioniche Promethazine; Histantil; Phenergan®; PMS-Promethazine

Pharmacologic Category

Antiemetic; Histamine H1 Antagonist

What key warnings should I know about before taking this medicine?

Do not give this medicine to a child younger than 2 years of age. Serious reactions may occur. Follow directions for use very closely and check all medicines with healthcare provider.

Reasons not to take this medicine

• Do not give this medicine to a child younger than 2 years of age.

• If you have an allergy to promethazine or any other part of this medicine.

• Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.

• If you have any of the following conditions: Asthma, bone marrow disease, or lung disease.

What is this medicine used for?

• This medicine is used to relieve allergy symptoms.

• This medicine is used to relieve motion sickness.

• This medicine is used to relieve pain.

• This medicine is used to treat anxiety.

• This medicine is used to treat sleep disorders.

How does it work?

• Promethazine blocks the allergic reaction by minimizing or preventing the body's reaction to the allergen.

• It affects the vomiting center in the brain.

• It calms the brain.

How is it best taken?

• Take this medicine 30 minutes before travel.

• Take tablet or liquid (syrup) with food.

• A liquid (syrup) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.

Suppository:

• Insert this medicine 30 minutes before travel if you are using it for motion sickness.

• Use suppository rectally.

• Remove foil wrapper.

• Insert suppository into the rectum with gentle pressure, pointed end first. Do not handle too much.

What do I do if I miss a dose? (does not apply to patients in the hospital)

• Use a missed dose as soon as possible.

• If it is almost time for the next dose, skip the missed dose and return to your regular schedule.

• Do not use a double dose or extra doses.

• Many times this medicine is taken on an as needed basis.

What are the precautions when taking this medicine?

• If you are 65 or older, use this medicine with caution. You could have more side effects.

• If you have seizures, talk with healthcare provider.

• Check medicines with healthcare provider. This medicine may not mix well with other medicines.

• Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and other pain medicine.

• You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you.

• You can get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen; wear protective clothing and eyewear.

• Tell healthcare provider if you are pregnant or plan on getting pregnant.

• Tell healthcare provider if you are breast-feeding.

What are some possible side effects of this medicine?

• Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert or have clear vision until you see how this medicine affects you.

• Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.

• Constipation. More liquids, regular exercise, or a fiber-containing diet may help. Talk with healthcare provider about a stool softener or laxative.

• Dry mouth. Frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.

What should I monitor?

• Change in condition being treated. Is it better, worse, or about the same?

• Dry mouth may cause an increase in cavities. Take good care of your teeth. See a dentist regularly.

Reasons to call healthcare provider immediately

• If you suspect an overdose, call your local poison control center or emergency department immediately.

• Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.

• Difficulty breathing.

• Fast heartbeat.

• Severe dizziness or passing out.

• Shakiness, difficulty moving around, or stiffness.

• Unable to pass urine.

• Any rash.

• No improvement in condition or feeling worse.

How should I store this medicine?

• Store tablets and liquid (syrup) at room temperature.

• Protect tablets and liquid (syrup) from light.

• Protect tablets from moisture. Do not store in a bathroom or kitchen.

• Store suppositories in a refrigerator.

General statements

• If you have a life-threatening allergy, wear allergy identification at all times.

• Do not share your medicine with others and do not take anyone else's medicine.

• Keep all medicine out of the reach of children and pets.

• Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).

• Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

• Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

Created: 2006-10-13 15:18:41.0

Modified: 2008-04-09 07:27:31.0

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